Dr. Reed’s research currently focuses on understanding the structure function relationship that impacts binding between iridium(III) complexes and G-quadruplex DNA. This is being explored computationally via molecular docking studies and in the lab by synthesizing a library of iridium complexes to test with GQ DNA. These luminescent compounds with good GQ affinity can be applied as label-free switch-on fluorescent detecting sensors for important analytes such as metal ions and small molecules.
Rochester ACS Women Chemists Committee Chair
Rochester ACS Executive Committee Member-at-Large
(2,9-Dimethyl-1,10-phenanthroline)bis[2-(pyridin-2-yl)phenyl] iridium(III) hexafluorophosphate and (2,9-dimethyl-1,10-phenanthroline)bis[5-methyl-2-(pyridin-2- yl)phenyl]iridium(III) hexafluorophosphate–diethyl ether–acetonitrile (1/0.61/0.78). Gienau, T.J.; Clay, M. ; Brennessel, W.W.; Carly R. Reed. Acta Cryst. E.2025, 81 (2), 127-131.
Modeling and NMR Data Elucidate the Structure of a G-Quadruplex–Ligand Interaction for a Pu22T-Cyclometalated Iridium(III) System. Carly R. Reed; Kennedy, S.D.; Horowitz, R.H.; Puthenpeedikakkal, A.M.K; Stern, H.A.; Mathews, D.H. Phys. Chem. B.2024, 128 (47), 11634-11643.
Assessing Technology’s Impact on General Chemistry Student Engagement During Covid-19. Robert J. LeSuer and Carly R. Reed. J Chem Ed. 2022, 99, 11, 3687.
Synthesis, crystal structure, electrochemical properties, and photophysical characterization of ruthenium(II) 4,4′-dimethoxy-2,2′-bipyridine polypyridine complexes. Santos, D.A.; Vu, A.T.; Brennessel, W.W.; Carly R. Reed; Garner, R.N. J.Coord. Chem.2022, https://doi.org/10.1080/00958972.2022.2066531.
Photoinitiated treatment of Mycobacterium using Ru(II) isoniazid complexes. Garner, R.N.; Pierce, C.G.; Carly R. Reed; Brennessel, W.W. Inorg. Chim. Acta. 2017, 461, 261.
The crystal structures of tetrakis(μ-n-butyrato-κ2O:O’)bis[bromidorhenium(III)] and tetrakis(μ-n-butyrato-κ2O:O’)bis[chloridorhenium(III)] acetonitrile disolvate. Carly R. Reed and William W. Brennesel. Acta. Cryst. E.2015, E71, 1480-1484.
Microwave synthesis of dirhenium paddlewheel complexes. Carly R. Reed; Feeney, C.; Merritt, M.A. J. Coord. Chem. 2015, 68, 3449.
Invited Panelist: Women Chemists Committee Luncheon at NERM 2022, Work Life Balance.
Talk: Carly R. Reed, Marcy A. Merritt, Callen Feeney, and William Brennessel, “Inorganic Microwave Synthesis: From Quadruple Bonds to Metal-Organic Frameworks,” invited seminar at SUNY Oswego, Oswego, NY, December 1, 2017.
Poster: Carly R. Reed, Samantha Klietz, Whitman Oehler-Marx, Marcy A. Merritt, Callen Feeney, William Brennessel, “Inorganic Microwave Synthesis: From Quadruple Bonds to Metal-Organic Frameworks,” 2017 Mid Atlantic Regional ACS Meeting, Hershey, PA, June 6, 2017.
Talk: Carly R. Reed, Marcy A. Merritt, Callen Feeney, and William Brennessel, “Inorganic Synthesis of Coordination Compounds: From Quadruple Bonds to Metal-Organic Frameworks,” invited seminar at Monroe Community College, Rochester, NY, February 7, 2017.
Rochester ACS Undergraduate Travel Awards Committee Member 2022
Rochester Women Chemists Committee Member 2021-2022
ACS Project SEED 2018 Summer I Faculty Mentor 2018
National Conference of Undergraduate Research Co-Advisor 2014 and 2017
